The isolation and nucleotide sequence of the complex AROM locus of Aspergillus nidulans.

نویسندگان

  • I G Charles
  • J W Keyte
  • W J Brammar
  • M Smith
  • A R Hawkins
چکیده

The AROM locus of A. nidulans, which governs five consecutive steps in pre-chorismate aromatic amino acid biosynthesis, has been cloned in a bacteriophage vector. The nucleotide sequence of the locus reveals a single, open reading-frame of 4,812 base-pairs, apparently without introns. An internal segment of the A. nidulans AROM sequence has extensive homology with the E. coli aroA gene that encodes the 5-enolpyruvylshikimate 3-phosphate synthase.

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عنوان ژورنال:
  • Nucleic acids research

دوره 14 5  شماره 

صفحات  -

تاریخ انتشار 1986